Thomas Cook has announced plans to close 21 stores - including their shop in Chesham - putting 320 jobs at risk.
The travel giant said that the closures are part of plans to "streamline" its UK retail network as part of an efficiency programme and to address changing customer behaviour.
A consultation process with the affected staff and unions has begun.
Thomas Cook's chief of tour operating Will Waggott said: "Today's announcement reflects the wider challenges seen on the high street, with more and more customers choosing to book online.
"These measures will help us to drive greater efficiencies across Thomas Cook so that we relentlessly focus our resources in those areas that give us the greatest opportunity to make a difference to customers in our core holiday offering.
"Looking ahead, we will be working to ensure that Thomas Cook is fit for the future, putting a rigorous focus on costs in a competitive environment while giving customers more reasons to holiday with the strongest brand in travel."
The stores listed for closure are:
Chesham, Buckinghamshire
Gosforth, Newcastle Upon Tyne
West Bromwich Sandwell Centre, West Midlands
Llandudno, North Wales
Sunderland Sainsbury's, Tyne & Wear
North Shields, Tyne & Wear
Peterlee, County Durham
Accrington, Lancashire
Market Harborough, 23 St Marys Place, Leicestershire
Bury Haymarket, Lancashire
Stratford-upon-Avon, Warwickshire
Aberdeen Langstane, Aberdeen
Launceston, Cornwall
Stevenage, Hertfordshire
Shipley, West Yorkshire
Cumbernauld, North Lanarkshire
Guildford, Surrey
Glenrothes, 52 Unicorn Way, Fife
Colchester High St, Essex
Kingston upon Thames, Surrey
Kirkintilloch Cowgate, Glasgow
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