A section of the A355 in Beaconsfield is due to shut today (Tuesday) as police carry out an "investigation and reconstruction".
It comes weeks after a 19-year-old from High Wycombe was killed on the same stretch of the road on Bank Holiday Monday - although police have yet to confirm if the reconstruction is in connection with Zaide Sandy's death.
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Transport for Bucks is urging people to avoid the area with a diversion via Candlemas Lane, Candlemas Mead and Ronald Road.
Transport for Bucks initially reported the road closure would be today (May 20), but signs at the scene say the closure will be on May 21 and TfB have since confirmed this.
Although the closure is set to be cleared ahead of rush hour, it is expected to still be in place at school pick-up time.
The estimated time that it will all be cleared is 4pm.
Police have been contacted to confirm more details about why the closure is taking place.
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