Wycombe Wanderers' FA Cup run came to a grinding halt as they were dispatched 5-1 by Championship side Preston North End at Adams Park.

A brace from Josh Harrop, two goals from Alan Browne and a deflected Daryl Horgan effort gave Alex Neil's side a very impressive victory in south Bucks.

Luke O'Nien gave Wycombe hope just before half-time to make it 2-1 but Preston were too strong for their League Two counterparts.

Harrop gave the visitors the perfect start when he scored a delightful free kick from 25 yards which gave Scott Brown no chance.

Browne then scored a wonderful half-volley on 38 minutes from 20 yards which he belted into the top corner after Joe Jacobson heroically cleared Horgan's cross.

O'Nien gave Wanderers belief on 43 minutes when he smashed home with the aid of a deflection after good work from Nick Freeman.

However, Preston stepped up a gear with Wanderers chasing the game and the superb Horgan saw his effort deflected in off Will De Havilland on 50 minutes to make it 3-1.

Browne then scored from the penalty spot on 76 minutes after Dan Scarr was harshly adjudged to have pulled Paul Huntington's shirt from a corner.

Harrop then finished the scoring on 86 minutes when he thumped home a header from Greg Cunningham's pinpoint cross.

The early goal knocked Wycombe out of their stride with the home side unable to exert any real pressure in the opening few minutes.

The visitors almost made it two on 13 minutes when they broke away down the left and Harrop got in behind but was denied by a superb stop from Brown.

Preston had a lot of pace going forward and Callum Robinson had a half-chance on 17 minutes from the edge of the box but put his effort high and wide.

Wanderers had the first sniff on 20 minutes when Adebayo Akinfenwa chested down for Matt Bloomfield but his volley was easily held by Declan Rudd.

Brown came to the rescue again on 22 minutes when Robinson lashed a firm shot at goal from 12 yards but Brown kept it out brilliantly with his legs.

The Chairboys, to their credit, were hanging on in there and Akinfenwa was giving the Preston backline plenty to think about from set-pieces.

Nick Freeman had an opportunity for the Blues on 31 minutes when Akinfenwa found the winger just inside the box but his shot deflected wide.

From the resulting corner, the ball fell to Freeman on the edge of the area but his half-volley flew over.

The Blues were beginning to find their feet and the dangerous Freeman crossed for Akinfenwa on 32 minutes but the big man’s header was off target.

Unfortunately, a hammer blow happened for Wanderers with Browne's magnificent strike before O'Nien gave the Blues a lifeline.

Wanderers came out with real purpose in the second half, playing at a higher tempo attempting to pin Preston back.

However, they were dealt a hammer blow with Horgan's goal before Robinson almost extended the Lilywhites’ advantage on 59 minutes but he stroked his shot just wide of the far post.

The goal knocked the stuffing out of the Chairboys and Ainsworth decided to bring on goal machine Scott Kashket for his first appearance of the campaign.

Horgan almost grabbed a second for himself on 71 minutes after a mistake by Dan Scarr but he was foiled by a fantastic save from the impressive Brown.

Preston were then awarded a debatable penalty which Browne slammed home before Harrop made it five with an expert header.

Kashket almost grabbed a dream goal on his comeback at the death but was denied by a smart save from Rudd.

Now, Wycombe have the league to focus on after yet another excellent FA Cup campaign.

WYCOMBE WANDERERS: Brown, Bean, El-Abd, Scarr, Jacobson (sub: Cowan-Hall, 77), O’Nien, Saunders (sub: De Havilland, 46), Bloomfield (sub: Kashket, 70), Freeman, Akinfenwa, Tyson. Subs: Ma-Kalambay, Gape, Southwell, Mackail-Smith.

PRESTON NORTH END: Rudd, Cunningham, Clarke, Horgan, Browne, Harrop, Woods (sub: Boyle, 77), Welsh, Huntington, Robinson (sub: Gallagher, 84), Bodin (sub: Johnson, 77). Subs: Hudson, Vermijl, O’Connor, Barkhuizen.

REFEREE: Peter Bankes